NCT03956433

Effect of Bioactive Enriched Food on Markers of Metabolic Syndrome

Investigation of the Effect of Daily Consumption of Bioactive Enriched Foods (BEFs) on Biochemical and Anthropometric Markers of the Metabolic Syndrome in Human Volunteers (a Pilot Study)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 35 (actual)
• Sponsor: University of Leeds · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This pilot study will investigate the enrichment type, in pancakes, most effective at improving markers of metabolic syndrome. Ready-made pancakes enriched with either docosahexaenoic acid (DHA), beta-glucan (BG) or anthocyanins (AC), alone or in combination of DHA+BG or DHA+AC, will be consumed for 4 weeks.

Detailed description

There is scientific evidence to support health claims that docosahexaenoic acid (DHA), an omega-3 fatty acid, and beta-glucan (BG), a soluble plant fibre, can help to maintain healthy cholesterol and triglyceride levels. It is also reported that anthocyanins (AC), colour pigments found in many dietary plants, can lower concentrations of low-density lipoprotein (LDL) cholesterol and increase high-density lipoprotein (HDL) cholesterol in dyslipidemic adults. Research studies often focus on bioactives administered as supplements, this study will also investigate the effectiveness of the food matrix. The project addresses the exploitation of bioactive compounds extracted from natural food sources that when added as ingredients to foods and consumed within the common diet, could significantly benefit human health and wellbeing.

Conditions

• Metabolic Syndrome

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Ready-made pancakes enriched with docosahexaenoic acid (DHA)	One portion of DHA-enriched pancakes will be eaten each day for 4 weeks.
DIETARY_SUPPLEMENT	Ready-made pancakes enriched with beta-glucan (BG)	One portion of BG-enriched pancakes will be eaten each day for 4 weeks.
DIETARY_SUPPLEMENT	Ready-made pancakes enriched with anthocyanins (AC)	One portion of AC-enriched pancakes will be eaten each day for 4 weeks.
DIETARY_SUPPLEMENT	Ready-made pancakes enriched with docosahexaenoic acid and beta-glucan (DHA+BG)	One portion of DHA+BG-enriched pancakes will be eaten each day for 4 weeks.
DIETARY_SUPPLEMENT	Ready-made pancakes enriched with docosahexaenoic acid and anthocyanins (DHA+AC)	One portion of DHA+AC-enriched pancakes will be eaten each day for 4 weeks.

Timeline

• Start date: 2014-09-01
• Primary completion: 2015-07-04
• Completion: 2015-07-04
• First posted: 2019-05-20
• Last updated: 2019-05-20

Locations

1 site across 1 country: United Kingdom