NCT03955809

Comparison the Effects of 3 Different Intraarticular Ketamine Doses on Postoperative Pain.

Effects of İntraarticular and Periarticular Applied Drugs on Postoperative Pain Management in Artroscopic Knee Surgery for

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 75 (actual)
• Sponsor: Balikesir University · Academic / Other
• Sex: —
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

the aim is to compare the effects of two different doses of intraarticular ketamine on postoperative pain scores and analgesic requirements.in knee artroscopy

Detailed description

All pateints are going to be operated under general anesthesia. At the end of the study patients are going to be randomyl seperated into 3 groups. The surgeon is going the following drugs intraarticulary. Group KL1: 0.5 mg/kg ketamin in % 0..9 NaCl at a total volume of 20 ml Group KL2: 1 mg/kg ketamin in % 0.9 NaCl at a total volume of 20 ml Group SL: 20 ml % 0.9 NaCl ll patients are going to receive a periarticula injection of 10 ml 0.5 bupivacaine and patient controlled analgesia with morphine. VAS scores and total analgesic requirement is going to be evaluated.

Conditions

• Arthroscopy

Interventions

Type	Name	Description
DRUG	Ketamine 0.5	İntrarticular Ketamine 0.5 mg/kg + 0.9 Nacl Total Volume 20 ml
DRUG	Ketamine 1	İntrarticular Ketamine 1 mg/kg + 0.9 NaCl Total Volume 20 ml
DRUG	% 0.9 NaCl	Intraarticular %0.9 NaCl

Timeline

• Start date: 2013-08-01
• Primary completion: 2014-08-01
• Completion: 2016-08-01
• First posted: 2019-05-20
• Last updated: 2020-01-22