Trials / Completed
CompletedNCT03953859
Embryo DNA Repair Capacity Project
Investigation of Cellular DNA Repair Capacity in Human Preimplantation Embryos
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 6 (actual)
- Sponsor
- Reproductive Medicine Associates of New Jersey · Academic / Other
- Sex
- All
- Age
- 21 Years – 42 Years
- Healthy volunteers
- —
Summary
The mail aim of the present study is to use molecular methods to analyze the ability of human preimplantation embryos to repair their DNA
Detailed description
The main aim of the present study is to investigate the DNA repair pathways of preimplantation embryos, examining the events that take place following induction of a DSB at a unique targeted site. The investigators aim to address questions concerning the functionality of the DNA repair mechanism(s) in developing embryos, before and after genome activation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | double strand break | an induction of a double strand break will be made in the embryos generated for this research and the repair mechanism observed |
Timeline
- Start date
- 2019-04-04
- Primary completion
- 2020-04-30
- Completion
- 2021-12-09
- First posted
- 2019-05-17
- Last updated
- 2022-01-14
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03953859. Inclusion in this directory is not an endorsement.