NCT03950596

Macroscopic and Molecular Changes in Knee Muscular-tendon Unit in Response to Acute Resistant Load

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Hillel Yaffe Medical Center · Other Government
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to determine the influence of acute resistance exercises on anatomical and biological changes in the quadriceps muscle and tendons of the knee

Conditions

• Quadriceps Muscle

Interventions

Type	Name	Description
OTHER	Acute resistant load exercises	Leg bench and leg press acute resistant load exercises Leg-bench and leg-press acute resistant load exercises
BEHAVIORAL	Background Questionnaire	Background questionnaire will be filled out by participants
OTHER	Pain Questionnaire	Pain questionnaire regarding pain in the knee during previous 3 months
GENETIC	DNA and RNA test	DNA and RNA tests will be sent to a genetic laboratory for analysis
DIAGNOSTIC_TEST	Ultrasound	Ultrasound of the knee joint and the quadriceps muscle and the pica tendon
DIAGNOSTIC_TEST	Percutaneous Needle Core Biopsy	Core Biopsy will be taken from the quadriceps femoris muscle

Timeline

• Start date: 2019-05-01
• Primary completion: 2020-05-01
• Completion: 2020-05-01
• First posted: 2019-05-15
• Last updated: 2019-05-15

Locations

1 site across 1 country: Israel