NCT03944629

Efficacy of Arnica Montana in Reducing Postoperative Edema and Pain

Efficacy of Arnica Montana in Reducing Postoperative Edema and Pain Following Third Molar Extraction

• Status: Completed
• Phase: —
• Study type: Interventional
• Enrollment: 53 (actual)
• Sponsor: Tufts University · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

This study is a prospective, randomized, double-blinded, controlled, clinical trial that evaluates the efficacy of using high potency homeopathic Arnica montana (SinEcch™) during the perioperative period for decreasing swelling and pain after extraction of partial or full/complete bony impacted third molars. The study group will be comprised of subjects who will receive homeopathic Arnica montana (SinEcch™) for perioperative management of edema and pain. The control group will be comprised of subjects who will receive matching SinEcch™ placebo (sugar pill).

Detailed description

Our study aims to look at the efficacy of homeopathic Arnica montana (SinEcch™) in reducing postoperative edema and pain. Pain will be measured using the visual analog scale (VAS). Swelling will be measured using a 3D imaging system. This is the first study using the 3D imaging system that looks at the effect of homeopathic Arnica montana in reducing facial swelling following the surgical removal of impacted third molars. Although SinEcch is marketed mainly for management of postoperative swelling and bruising, Arnica Montana has been used for managing the sequelae of postoperative inflammation including pain so one of the secondary outcome measure for this study is to measure the efficacy of SinEcch in management of post-operative pain.

Conditions

• Arnica
• Third Molar Extraction

Interventions

Type	Name	Description
DRUG	SinEcch	The study group will be comprised of subjects who will receive homeopathic Arnica montana (SinEcch™) for perioperative management of edema and pain.
OTHER	Placebo	The control group will be comprised of subjects who will receive matching SinEcch™ placebo (sugar pill).

Timeline

• Start date: 2018-01-26
• Primary completion: 2022-06-14
• Completion: 2022-06-14
• First posted: 2019-05-09
• Last updated: 2026-01-29
• Results posted: 2026-01-29

Locations

1 site across 1 country: United States