Trials / Completed
CompletedNCT03939403
Conventional Ovarian Stimulation vs. Single Injection Stimulation of Corifollitropin Alfa in Oocyte Donor
Conventional Ovarian Stimulation vs. Single Injection Stimulation of Corifollitropin Alfa in Oocyte Donor. A Randomized Clinical Trial. TAIL Study
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 180 (actual)
- Sponsor
- Instituto Bernabeu · Academic / Other
- Sex
- Female
- Age
- 18 Years – 32 Years
- Healthy volunteers
- Accepted
Summary
This study aims to study the efficiency of using a single injection of Corifollitropin alfa for ovarian stimulation by initiating administration late and without further administration of follicle-stimulating hormone after the 7th day of stimulation compared to conventional ovarian stimulation using Corifollitropin alfa (drug administration 5 days after cessation of hormonal contraceptive and supplementation with follicle-stimulating hormone daily administration from the 8th day of stimulation). This a controlled randomized clinical study and 180 patients will be recruited (90 per arm) and the primary study outcome is the number of obtained oocytes.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Time of administration of Corifollitropin Alfa | The used treatment will be identical in both arms. The difference between the groups will be the moment of beginning of the stimulation as well as the later administration of more FSH activity. The control grup will receive the treatment on the 5th day after the cessation of hormonal contraceptive use. The used treatment will be identical in both arms. The difference between the groups will be the moment of beginning of the stimulation as well as the later administration of more FSH activity. The intervention grup will receive the treatment on the 7th day after the cessation of hormonal contraceptive use. |
Timeline
- Start date
- 2019-11-18
- Primary completion
- 2021-05-08
- Completion
- 2021-05-08
- First posted
- 2019-05-06
- Last updated
- 2021-05-19
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT03939403. Inclusion in this directory is not an endorsement.