NCT03938402

Intraocular Pressure and Optic Nerve Sheath Diameter Changes at Different PEEP Levels

Intraocular Pressure and Optic Nerve Sheath Diameter Changes at Different Positive End-expiratory Pressure Applications in Laparotomic Surgery

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Marmara University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Positive end-expiratory pressure (PEEP) is sometimes used during perioperative period, as it has favourable effects on lung mechanics. Unfortunately, it has some negative effects on the patients, like increased intraabdominal, intrathoracic, intracranial and intraocular pressures. In this study the investigators aimed to investigate the effects of different PEEP levels on the patients' intraocular and intracranial pressures. Intraocular pressure will be measured by ocular tonometry, and intracranial pressure will be estimated by optic nerve sheath diameter measurement. The measurements will be performed in the operating room in the patients undergoing laparotomic surgery.

Conditions

• Intraocular Pressure
• Intracranial Pressure
• Positive End-expiratory Pressure

Interventions

Type	Name	Description
OTHER	Positive end-expiratory pressure	Different levels of positive end-expiratory pressure (i.e., 5, 10 and 15 cm H2O) will be applied to the groups.

Timeline

• Start date: 2019-07-01
• Primary completion: 2020-12-31
• Completion: 2020-12-31
• First posted: 2019-05-06
• Last updated: 2021-12-03

Locations

1 site across 1 country: Turkey (Türkiye)