Trials / Completed
CompletedNCT03936140
The Effect of Iloprost on Oxygenation During One-lung Ventilation for Lung Surgery
The Effect of Iloprost on Arterial Oxygenation and Shunt Fraction During One-lung Ventilation for Lung Surgery
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 72 (actual)
- Sponsor
- Seoul St. Mary's Hospital · Academic / Other
- Sex
- All
- Age
- 20 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
During one-lung ventilation in patients undergoing thoracic surgery, the persistent flow in the non-ventilated lung increases intrapulmonary shunt and decreases systemic arterial oxygenation. This prospective, randomized, double blind study was conducted to evaluate the effects of inhaled iloprost during one-lung ventilation on arterial oxygenation and shunt fraction during thoracic surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Inhaled iloprost | Study drug was inhaled to ventilated lung through a nebulized system in inspiratory limb after one-lung ventilation in the lateral decubitus position. |
| DRUG | Distilled water | Study drug was inhaled to ventilated lung through a nebulized system in inspiratory limb after one-lung ventilation in the lateral decubitus position. |
Timeline
- Start date
- 2018-01-04
- Primary completion
- 2018-10-24
- Completion
- 2018-10-24
- First posted
- 2019-05-03
- Last updated
- 2019-05-03
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT03936140. Inclusion in this directory is not an endorsement.