NCT03934970

Diffusion Tensor Imaging of Median Nerve in Diabetic Peripheral Neuropathy

A Study of Diffusion Tensor Imaging of Median Nerve in Diabetic Peripheral Neuropathy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 45 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study is a diagnostic accuracy study that aims to evaluate the role of DTI in evaluation of DPN in comparison to clinical scores and nerve conduction studies (NCS). The study included 30 patients with diabetes mellitus complaining of neuropathy symptoms and 15 healthy volunteers. All subjects underwent evaluation using 1.5T DTI of median nerves and NCS. Patients underwent clinical evaluation using Neuropathy Deficit Score (NDS), Neuropathy Impairment Score in the Lower Limbs (NIS-LL) and Diabetic Neuropathy Examination (DNE) score. The values of these tests were compared and correlated and diagnostic accuracy tests were performed together with identification of cut-off score for abnormal diffusion tensor imaging parameters in diabetic neuropathy

Conditions

• Diabetic Polyneuropathy
• Magnetic Resonance Imaging

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Diffusion tensor imaging of peripheral nerves	All subjects underwent evaluation using 1.5T DTI of median nerves and NCS. Patients underwent clinical evaluation using Neuropathy Deficit Score (NDS), Neuropathy Impairment Score in the Lower Limbs (NIS-LL) and Diabetic Neuropathy Examination (DNE) score.

Timeline

• Start date: 2015-04-30
• Primary completion: 2015-11-30
• Completion: 2015-11-30
• First posted: 2019-05-02
• Last updated: 2019-05-03

Locations

1 site across 1 country: Egypt