NCT03934710

Mood Effects of Serotonin Agonists Extended

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 56 (actual)
• Sponsor: University of Chicago · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

In this study we are examining the effects of repeated very low doses of serotonin agonists on mood individuals with negative mood.

Detailed description

Here, we are examining the effects of four repeated low doses of lysergic acid diethylamide (LSD), compared to placebo, administered to healthy adults at 3-4 day intervals, on mood, cognitive performance and responses to emotional tasks

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Placebo	Drug will be administered in solution form
DRUG	Serotonin agonist - 13ug	13ug lysergic acid diethylamide
DRUG	Serotonin agonist - 26ug	26ug lysergic acid diethylamide

Timeline

• Start date: 2019-04-20
• Primary completion: 2021-06-07
• Completion: 2021-06-07
• First posted: 2019-05-02
• Last updated: 2023-11-29
• Results posted: 2023-11-29

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study