Trials / Completed
CompletedNCT03934632
The Impact of Leg Immobilization on Postabsorptive and Postprandial Muscle Protein Breakdown in Healthy Young Males
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 24 (actual)
- Sponsor
- University of Exeter · Academic / Other
- Sex
- Male
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
The present study will seek the quantify the simultaneous muscle protein synthesis and breakdown response with and without amino acid provision in humans following 2 days of immobilisation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Postabsorptive | Saline will be infused to mimic postabsorptive circulating amino acid concentrations |
| OTHER | Postprandial | An amino acid infusate will be administered to mimic postprandial circulating amino acid concentrations |
| PROCEDURE | Immobilisation | One leg will undergo 2 days immobilisation prior to the test day |
Timeline
- Start date
- 2019-04-15
- Primary completion
- 2020-03-17
- Completion
- 2023-01-09
- First posted
- 2019-05-02
- Last updated
- 2023-03-22
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT03934632. Inclusion in this directory is not an endorsement.