Trials / Completed
CompletedNCT03933605
Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Comparison of Palonosetron With Combined Palonosetron and Midazolam for Preventing Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 88 (actual)
- Sponsor
- Yeungnam University College of Medicine · Academic / Other
- Sex
- Female
- Age
- 20 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
In the present study, midazolam and palonosetron in combination were more effective than palonosetron alone in lowering the incidence and severity of postoperative nausea and vomiting in the initial 2 h after laparoscopic cholecystectomy. Postoperative clinical complications were not different in both groups.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | midazolam and palonosetron group | intravenous midazolam and palonosetron administraion as prevention of postoperative nausea and vomiting |
| DRUG | palonosetron group | intravenous palonosetron administraion as prevention of postoperative nausea and vomiting |
Timeline
- Start date
- 2017-07-10
- Primary completion
- 2019-02-01
- Completion
- 2019-02-08
- First posted
- 2019-05-01
- Last updated
- 2019-05-01
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT03933605. Inclusion in this directory is not an endorsement.