NCT03932942

Point-of-care Testing of Respiratory Pathogens at Pediatric Emergency Room

Impact of Multiplex Respiratory Pathogen Testing on Antimicrobial Consumption and Hospital Admissions at Pediatric Emergency Room: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,350 (actual)
• Sponsor: University of Oulu · Academic / Other
• Sex: All
• Age: 17 Years
• Healthy volunteers: Not accepted

Summary

The main objective of the trial is to evaluate the effect of point-of-care testing of respiratory pathogens at a pediatric emergency room on the antibiotic consumption and hospital admissions in acutely ill children.

Detailed description

The study is a randomized controlled trial including children 0 up to 17 years of age with fever or acute respiratory infection at a pediatric emergency department in university hospital. In total 1668 subjects will be randomly allocated to undergo point-of-care multiplex respiratory pathogen testing with results ready within approximately one hour or to a control group with testing according to clinical judgement and results ready within next office day. Subjects will be randomized on admission and unequal allocation ratio of 2:1 (1112 subjects to intervention and 556 subjects to control arm) will be used. Data on rate of hospitalization, antibiotic prescriptions, ancillary testing and length of visit will be collected using medical record system.

Conditions

• Respiratory Tract Infections

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	QIAstat at pediatric emergency room	Pediatric acute care nurses will obtain respiratory samples for testing from all patients with fever or any respiratory symptom.

Timeline

• Start date: 2019-05-06
• Primary completion: 2020-03-20
• Completion: 2020-04-13
• First posted: 2019-05-01
• Last updated: 2020-11-04

Locations

1 site across 1 country: Finland