Clinical Trials Directory

Trials / Completed

CompletedNCT03930641

Study of the Safety of Brolucizumab 6 mg in Prefilled Syringe in Patients With Neovascular Age Related Macular Degeneration

An Open-Label, Single-Arm, Multicenter, Phase IIIb Study in Patients With Neovascular Age-Related Macular Degeneration to Evaluate the Safety of Brolucizumab 6 mg in Prefilled Syringe

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
34 (actual)
Sponsor
Novartis Pharmaceuticals · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

This was a multicenter, open label study that is designed to evaluate the safety of brolucizumab 6 mg in a prefilled syringe in subjects with neovascular age related macular degeneration and to support collection of observations of the prefilled syringe use for intravitreal injection.

Detailed description

The primary objective of this study was to evaluate the safety of brolucizumab 6 mg delivered in a pre-filled syringe (PFS) in subjects with neovascular age-related macular degeneration (nAMD) with the primary endpoint being the incidence of ocular and non-ocular adverse events (AEs). There were no other objectives for this study.

Conditions

Interventions

TypeNameDescription
DRUGRTH2586 mg in prefilled syringe

Timeline

Start date
2019-05-23
Primary completion
2019-07-02
Completion
2019-07-02
First posted
2019-04-29
Last updated
2021-01-05
Results posted
2020-08-03

Locations

3 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03930641. Inclusion in this directory is not an endorsement.