Clinical Trials Directory

Trials / Completed

CompletedNCT03928704

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Nonradiographic Axial Spondyloarthritis

A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Bimekizumab in Subjects With Active Nonradiographic Axial Spondyloarthritis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
274 (actual)
Sponsor
UCB Biopharma SRL · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to demonstrate the efficacy, safety and tolerability of bimekizumab administered subcutaneously (sc) compared to placebo in the treatment of subjects with active nonradiographic axial spondyloarthritis (nr-axSpA).

Conditions

Interventions

TypeNameDescription
DRUGBimekizumabSubjects will receive bimekizumab at pre-specified time-points.
OTHERPlaceboSubjects will receive placebo at pre-specified time-points during the Double-Blind Treatment Period.

Timeline

Start date
2019-04-25
Primary completion
2022-06-29
Completion
2023-04-17
First posted
2019-04-26
Last updated
2025-12-24
Results posted
2024-11-13

Locations

83 sites across 13 countries: United States, Belgium, Bulgaria, China, Czechia, France, Germany, Hungary, Japan, Poland, Spain, Turkey (Türkiye), United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT03928704. Inclusion in this directory is not an endorsement.