NCT03922919

Effect of Administration of 3rd Generation Cephalosporin on the Digestive Carrying of 3rd Generation Cephalosporin-resistant Enterobacteriaceae (CEF-IMPACT)

Effect of Administration of 3rd Generation Cephalosporin (Ceftriaxone Versus Cefotaxime) on the Digestive Carrying of 3rd Generation Cephalosporin-resistant Enterobacteriaceae (EB C3G-R)

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 250 (estimated)
• Sponsor: Centre Hospitalier Universitaire de Besancon · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study was to compare the frequency of occurrence of digestive carrying of 3rd generation cephalosporin-resistant enterobacteriaceae (EB C3G-R), acquired during hospitalization in one of the participating departments, between patients treated with ceftriaxone and patients treated with cefotaxime

Conditions

• Infectious Disease - Resistant Enterobacteriaceae (Diagnosis)

Interventions

Type	Name	Description
DRUG	Cefotaxime Injection	Systematic use of cefotaxime.
PROCEDURE	Rectal swab	Rectal swab every 3 days during hospitalization and then 30 days after the first antibiotic infusion
DRUG	Cefotaxime/ceftriaxone	ceftriaxone or cefotaxime infusion at the discretion of the prescribing physician

Timeline

• Start date: 2018-04-03
• Primary completion: 2020-04-03
• Completion: 2020-10-01
• First posted: 2019-04-22
• Last updated: 2019-04-22

Locations

1 site across 1 country: France