NCT03921320

Compensatory Sweating After Unilateral Sympathectomy on the Dominant Side or Bilateral Sequential Sympathectomy

Evaluation of Compensatory Sweating After Unilateral Videothoracoscopic Sympathectomy of the Dominant Side or Sequential Bilateral Videothoracoscopic Sympathectomy: a Multicentric Randomized Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: University of Sao Paulo · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The standard treatment for palmar hyperhidrosis is bilateral sequential thoracic sympathectomy. High rates of compensatory sweating due to the surgical procedure are described in the literature. In the search for a reduction in this side effect, it is possible that unilateral sympathectomy in the dominant side obtains acceptable results and leads to less compensatory sweating with improvement of the quality of life. The aim of this study it to compare the intensity of compensatory sweating due to the standard treatment, that is, bilateral sequential videothoracoscopic sympathectomy in relation to unilateral thoracic sympathectomy on the dominant side.

Conditions

• Hyperhidrosis Primary Focal Palms

Interventions

Type	Name	Description
PROCEDURE	Bilateral sequential sympathectomy	Bilateral videothoracoscopic sequential R4 sympathectomy
PROCEDURE	Unilateral sympathectomy	Unilateral videothoracoscopic R4 sympathectomy in dominant side (right side)
PROCEDURE	Contralateral sympathectomy	Contralateral (left side) videothoracoscopic R4 sympathectomy

Timeline

• Start date: 2019-03-07
• Primary completion: 2023-06-01
• Completion: 2023-12-01
• First posted: 2019-04-19
• Last updated: 2021-10-12

Locations

10 sites across 1 country: Brazil