Clinical Trials Directory

Trials / Completed

CompletedNCT03919578

Protectivity and Safety Following Recombinant Hepatitis B Vaccine

Protectivity and Safety Following Recombinant Hepatitis B Vaccine With Different Source of Hepatitis B Bulk Compared to Hepatitis B (Bio Farma) Vaccine in Indonesian Population

Status
Completed
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
536 (actual)
Sponsor
PT Bio Farma · Industry
Sex
All
Age
10 Years – 40 Years
Healthy volunteers
Accepted

Summary

Protectivity and Safety Following Recombinant Hepatitis B Vaccine with different source of Hepatitis B bulk compared to Hepatitis B (Bio Farma) vaccine in Indonesian Population

Detailed description

Protectivity and Safety Following Recombinant Hepatitis B Vaccine with different source of Hepatitis B bulk compared to Hepatitis B (Bio Farma) vaccine in Indonesian Population. Experimental, randomized, double blind, four arm parallel group study, lot to lot consistency study.

Conditions

Interventions

TypeNameDescription
BIOLOGICALRecombinant Hepatitis B vaccineRecombinant Hepatitis B vaccine is an inactivated HbsAg produced in yeast cells (Hansenula polymorpha) using recombinant DNA technology. It is a whitish liquid produced by culture genetically engineered yeast cell which carry the relevant gene of the HbsAg. The inactivated HbsAg (bulk) is imported from Serum Institute of India and then formulated and filled at Bio Farma.
BIOLOGICALRecombinant Hepatitis B (Bio Farma)Recombinant Hepatitis B vaccine is an inactivated HbsAg produced in yeast cells (Hansenula polymorpha) using recombinant DNA technology. It is a whitish liquid produced by culture genetically engineered yeast cell which carry the relevant gene of the HbsAg. The inactivated HbsAg (bulk) is imported from The Janssen Vaccine Corp and then formulated and filled at Bio Farma.

Timeline

Start date
2019-09-11
Primary completion
2020-01-30
Completion
2020-02-28
First posted
2019-04-18
Last updated
2022-09-19

Locations

1 site across 1 country: Indonesia

Source: ClinicalTrials.gov record NCT03919578. Inclusion in this directory is not an endorsement.