Clinical Trials Directory

Trials / Completed

CompletedNCT03918109

OTO-313 in Subjects With Subjective Tinnitus

A Randomized, Double-blind, Placebo-controlled Phase 1/2 Study of OTO-313 Given as a Single Intratympanic Injection in Subjects With Subjective Tinnitus

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
43 (actual)
Sponsor
Otonomy, Inc. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the safety, tolerability, plasma pharmacokinetics (PK), and exploratory efficacy of OTO-313 administered as an intratympanic injection for the treatment of subjective tinnitus.

Conditions

Interventions

TypeNameDescription
DRUGOTO-313single intratympanic injection of gacyclidine
DRUGPlacebosingle intratympanic injection of placebo

Timeline

Start date
2019-04-04
Primary completion
2020-05-29
Completion
2020-05-29
First posted
2019-04-17
Last updated
2022-12-23
Results posted
2022-12-23

Locations

16 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03918109. Inclusion in this directory is not an endorsement.