NCT03917394

Erythropoietin And/Or Iron Sucrose For Perioperative Anemia Management In Hip and Knee Arthroplasty

Efficacy and Safety of Erythropoietin And/Or Intravenous Iron Sucrose For Treatment of Anemia In Hip and Knee Arthroplasty: A Single-center Retrospective Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 780 (estimated)
• Sponsor: Peking Union Medical College Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Perioperative anemia is very common in patients undergoing total hip arthroplasty (THA) and total knee arthroplasty (TKA). This study retrospectively analyzes the use of rHuEPO and iron sucrose in patients undergoing total hip and knee arthroplasty in order to observe the short-term efficacy and safety of rHuEPO and iron sucrose.

Detailed description

This study aims to explore whether short-term use of rHuEPO and iron sucrose can improve postoperative anemia and promote postoperative rehabilitation after hip and knee arthroplasty. According to different therapies of perioperative anemia , included subjects would be divided into rHuEPO monotherapy group, iron sucrose monotherapy group, rHuEPO combined with iron sucrose group and control group (without rHuEPO and iron sucrose).

Conditions

• Anemia, Iron Deficiency

Interventions

Type	Name	Description
DRUG	rHuEPO	rHuEPO was administrated daily with 10000 IU or 20000 IU
DRUG	Iron sucrose	Iron sucrose was administrated daily with 100mg or 200mg

Timeline

• Start date: 2019-04-24
• Primary completion: 2019-05-30
• Completion: 2019-09-30
• First posted: 2019-04-17
• Last updated: 2019-04-25

Locations

1 site across 1 country: China