Clinical Trials Directory

Trials / Completed

CompletedNCT03917199

Utility of Regadenoson Low-dose Dynamic Computed Tomography for Myocardial Perfusion Assesment (ULYSSES Study).

Status
Completed
Phase
Study type
Observational
Enrollment
60 (actual)
Sponsor
National Institute of Cardiology, Warsaw, Poland · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The ULYSSES study is a single-center, prospective study aimed at evaluation of myocardial ischemia using regadenoson low-dose dynamic computed tomography myocardial perfusion imaging (CTP) in patients diagnosed with intermediate coronary artery stenoses in referrence to the magnetic resonance myocardial perfusion imaging (MR MPI).

Detailed description

The ULYSSES study is a single-center, prospective study aimed at evaluation of myocardial ischemia using regadenoson low-dose dynamic computed tomography myocardial perfusion (CTP) in patients diagnosed with intermediate coronary artery stenoses in referrence to the magnetic resonance myocardial perfusion imaging (MR MPI). The main objectives of the study are: * to evaluate feasibility of low - dose regadenoson dynamic computed tomography myocardial imaging protocol * to assess the diagnostic value of quantitative dynamic CTP based absolute parameters (myocardial blood flow - MBF, myocardial blood volume - MBV, perfused capillary blood volume - PCBV, peak value - PV, time to peak - TTP) in reference to magnetic resonance myocardial perfusion imaging * to assess the diagnostic value of quantitative dynamic CTP based relative parameters (relative myocardial blood flow - MBFR, relative myocardial blood volume - MBVR, relative perfused capillary blood volume - PCBVR, relative peak value - PVR, relative time to peak - TTPR) in reference to magnetic resonance myocardial perfusion imaging * evaluation of safety of regadenoson low-dose dynamic CTP.

Conditions

Timeline

Start date
2016-11-01
Primary completion
2019-07-01
Completion
2019-07-11
First posted
2019-04-16
Last updated
2019-09-17

Locations

1 site across 1 country: Poland

Source: ClinicalTrials.gov record NCT03917199. Inclusion in this directory is not an endorsement.