NCT03916133

Analysis of Selective Cerebrovascular Distribution With FDCT in the Angiosuite

Evaluation of the Clinical Feasibility of Angiographic Flat-detector CT (FDCT) Perfusion Imaging (6sPBV) Technique.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 127 (actual)
• Sponsor: University Hospital, Antwerp · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to evaluate the clinical feasibility of the angiographic Flat Detector CT perfusion imaging (6s PBV) technique. The investigators will examine the specific vessel distribution of patients with steno-occlusive disease, treated with a surgical extracranial-intracranial bypass and assess the cerebral perfusion during test occlusion upon a neurovascular treatment and in intracranial tumor patients referred for potential pre-operative embolization. This study encompasses three scientific objectives: 1. What is the selective contribution of an individual bypass artery to the brain perfusion? 2. Is a selective intra-arterial angiographic perfusion examination useful in the decision-making of performing pre-operative embolization of intracranial tumors? 3. What is the usefulness of performing additive 6s PBV images compared to classical 2D angiography and/or clinical neurological evaluation in case of test occlusion in the evaluation of possible mother vessel occlusion in treatment of complex neurovascular diseases?

Conditions

• Ischemic Stroke
• Intracranial Aneurysm
• Intracranial Arterial Diseases
• Cerebral Hypoxia
• Intracranial Vascular Disorder

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Intervention group	6s PBV mapping will be conducted

Timeline

• Start date: 2018-06-01
• Primary completion: 2020-12-01
• Completion: 2021-01-01
• First posted: 2019-04-16
• Last updated: 2022-05-17

Locations

1 site across 1 country: Belgium