NCT03912922

SIT LESS 4: How Does Reducing Sitting Time Improve Glucose and Lipid Metabolism?

SIT LESS 4: How Does Reducing Sitting Time Improve Glucose and Lipid Metabolism? A Study to Identify Underlying Mechanisms

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Maastricht University Medical Center · Academic / Other
• Sex: Female
• Age: 45 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Research has shown that replacing sitting time with low intensity physical activity (such as slowly walking and standing) has beneficial effects on metabolic health, like insulin sensitivity, comparable to improvements after sitting all day in combination with 1h streneous exercise. The main objective of this study is to investigate the underlying mechanisms responsible for improved insulin sensitivity after 4 days of sitting less compared to sitting and exercise in healthy obese women. Our secondary objective is to investigate the effects of sitting less on cardio metabolic parameters.

Conditions

• Overweight and Obesity

Interventions

Type	Name	Description
OTHER	Activity regime	Activity regime of 4 days followed by a test day.

Timeline

• Start date: 2017-12-15
• Primary completion: 2020-03-13
• Completion: 2020-03-13
• First posted: 2019-04-11
• Last updated: 2021-01-20

Locations

1 site across 1 country: Netherlands