Trials / Completed
CompletedNCT03911232
The Improvement of Intraoperative Neuromonitoring of Recurrent Laryngeal Nerve
The Improvement of Intraoperative Neuromonitoring of Recurrent Laryngeal Nerve During Thyroid Surgery
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital · Academic / Other
- Sex
- All
- Age
- 20 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Objectives: The use of neuromuscular blocking agent may interfere with the function of intraoperative neuromonitoring (IONM) in thyroid surgery.
Detailed description
An enhanced neuromuscular-blockade (NMB) recovery protocol was investigated in a clinically applied during thyroid neural monitoring surgery. In as subsequent clinical application study, 60 patients who underwent thyroidectomy with IONM followed an enhanced NMB recovery protocol- rocuronium 0.6 mg/kg at anesthesia induction and sugammadex 2 mg/kg at operation start. Train-of-four (TOF) ratio was used for continuous quantitative monitoring of neuromuscular transmission.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | sugammadex | standard general anesthesia protocol with sugammadex |
Timeline
- Start date
- 2015-03-01
- Primary completion
- 2016-03-01
- Completion
- 2016-03-01
- First posted
- 2019-04-11
- Last updated
- 2021-06-30
Locations
1 site across 1 country: Taiwan
Source: ClinicalTrials.gov record NCT03911232. Inclusion in this directory is not an endorsement.