NCT03909035

A Collaborative Approach to Medication Reviews for Older Patients With Polypharmacy

Medication Reviews Performed for Elderly Patients: a Collaborative Approach Between Community Pharmacists, Patients and General Practitioners to the Optimizations of Prescriptions

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 697 (actual)
• Sponsor: University Hospital, Toulouse · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

In patients aged 65 years and older, polypathology is frequent and often associated with polypharmacy. This polypharmacy may be a source of iatrogeny due to pharmacokinetic interactions, enhanced sensitivity of older people to medication, or failure to adhere to the therapy. Since January 2018, French community pharmacists have been allowed by the Health ministry to perform medication reviews for people aged 65 years and over, who are being treated with more than 5 medications a day. the present hypothesis is that medication therapy management performed in collaboration with patients, general practitioners, and community pharmacists will lead to a reduction in medical events and inappropriate prescriptions.

Detailed description

This is a stepped-wedge cluster randomised controlled trial conducted in 9 regions of France. Each region represents one cluster with 7 community pharmacies located around the University Hospital associated with that cluster. In total, 63 community pharmacies will be enrolled, with each pharmacy including 20 patients over a 10 month-period. Over the life-time of the project, a total of 1260 patients will benefit from either the intervention or from a controlled pharmaceutical care according to the period of time they will be enrolled.

Conditions

• Medication Therapy Management

Interventions

Type	Name	Description
OTHER	Medication therapy management	The intervention is in the form of a pharmacist-led medication review aimed at detecting potentially inappropriate prescribing. It includes: * A patient-pharmacist interview to collect comorbidities, medication, laboratory results, self-medication, adherence, medication patient's knowledge. * A pharmacist's evaluation of the prescriptions based on the patient's conditions and on the current recommendations for clinical practice. * Detailed feedback to the general practitioner. * An appointment with the patient to explain the modifications made by the general practitioner (GP)

Timeline

• Start date: 2019-06-03
• Primary completion: 2021-10-25
• Completion: 2021-10-25
• First posted: 2019-04-09
• Last updated: 2023-11-14

Locations

1 site across 1 country: France