NCT03908736

Thinking Zinc: a Study of Zinc Supplements on the Navajo Nation

Thinking Zinc: A Study of Zinc Supplementation to Ameliorate Adverse Effects of Mine Waste Exposure on the Navajo Nation

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University of New Mexico · Academic / Other
• Sex: All
• Age: 21 Years – 64 Years
• Healthy volunteers: Accepted

Summary

This is a study to assess the effect of dietary zinc supplementation to mitigate biomarkers of metal toxicity in exposed tribal populations.

Detailed description

Communities living in proximity to abandoned uranium mines have documented exposures to metals in drinking water, soil and dust. Exposure to these metals, principally uranium and arsenic, and metal mixtures is associated with dysregulation of immune function and other health effects. The objective of this study is to conduct an intervention trial to assess the effect of dietary zinc supplementation to mitigate the toxicity of metal exposures. The current project is part of a larger research effort funded by the NIH Superfund Program to study environmental metals exposures in tribal communities in New Mexico.

Conditions

• DNA Damage
• Immune System Disorder

Interventions

Type	Name	Description
DRUG	Zinc Picolinate 15 Mg	zinc picolinate, 15 mg/day for 6 months

Timeline

• Start date: 2019-05-19
• Primary completion: 2027-07-01
• Completion: 2027-12-01
• First posted: 2019-04-09
• Last updated: 2025-05-20

Locations

1 site across 1 country: United States