Trials / Active Not Recruiting
Active Not RecruitingNCT03907735
Oxytocin Receptor Expression in Pregnancy
Oxytocin Receptor Expression in Pregnancy: When Does it Turn on
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 30 (estimated)
- Sponsor
- Oregon Health and Science University · Academic / Other
- Sex
- Female
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
This study aims to determine when during gestation oxytocin receptor (OXTR) expression increases in the myometrium, which will contribute new insight to the management of obstetric hemorrhage and our understanding of normal and abnormal labor.
Detailed description
In this descriptive study, we will obtain myometrial tissue samples by core needle biopsy under ultrasound guidance in anesthetized women immediately following surgical abortion and from controls, all of whom are undergoing a separate planned obstetric/gynecologic surgery. Tissue studies will be performed on these biopsy samples to examine oxytocin receptor expression and function.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Myometrial tissue sample collection | Myometrial tissue samples by core needle biopsy under ultrasound guidance |
Timeline
- Start date
- 2019-06-03
- Primary completion
- 2020-08-22
- Completion
- 2025-08-01
- First posted
- 2019-04-09
- Last updated
- 2025-05-31
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03907735. Inclusion in this directory is not an endorsement.