NCT03905252

Biomarkers for Human Heart Failure

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 535 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to establish the various ranges of proteins that can be assayed in the plasma and urine from hospitalized patients with all classes of heart failure and/or STEMI (ST-segment elevation myocardial infarction)/NSTEMI (Non-ST-segment elevation myocardial infarction), as well as history reviews.

Detailed description

Schematic Design of the Study: Single blood draw, one random urine and 24-hr urine collection from hospitalized patients with chronic/acute heart failure and/or STEMI-NSTEMI. If there should be a subsequent hospitalization,another collection of a 45 ml blood sample, random urine and one 24-hour urine collection may be completed if indicated at initial hospitalization. Aims: The purpose of this study is to attempt to establish the various ranges of proteins that can be assayed from the plasma and urine of patients with all classes of heart failure and MI (myocardial infarction). Follow-up hospitalizations may result in another 45 ml blood draw, random urine and 24-hr. urine collection to evaluate the outcome of the heart failure treatment used with the previous hospitalization, if indicated in consent. A history review will be necessary as well.

Conditions

• CHF

Interventions

Type	Name	Description
OTHER	sample analysis	blood, Random urine sample and 24-hour urine samples

Timeline

• Start date: 2009-08-01
• Primary completion: 2024-02-01
• Completion: 2024-02-01
• First posted: 2019-04-05
• Last updated: 2024-05-28

Locations

1 site across 1 country: United States