Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT03904316

Use of Biodesign® Otologic Graft in Tympanoplasty

Use of Biodesign® Otologic Graft in Tympanoplasty: A Prospective, Randomized Trial

Status
Withdrawn
Phase
Phase 4
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Henry Ford Health System · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a prospective, randomized trial to evaluate tympanoplasty outcomes using Biodesign SIS graft compared to autologous temporalis fascia, the most commonly used graft for repair of tympanic membrane.

Detailed description

Patients 18 years or older will undergo primary tympanoplasty without mastoidectomy. The patients will be randomized into groups receiving Biodesign versus autograft temporalis fascia for repair.

Conditions

Interventions

TypeNameDescription
BIOLOGICALBiodesign Otologic graftAcellular matrix derived from porcine small intestine submucosa
OTHERAutologous temporalis fasciaAn autologous graft for tympanic membrane repair

Timeline

Start date
2018-10-03
Primary completion
2022-07-01
Completion
2022-07-01
First posted
2019-04-05
Last updated
2025-12-19

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03904316. Inclusion in this directory is not an endorsement.