Trials / Recruiting
RecruitingNCT03900780
Preimplantation Genetic Testing for Aneuploidies in Patients With Recurrent Implantation Failure
Preimplantion Genetic Testing for Aneuploidies (PGT-A) in Patients With Recurrent Implantation Failure: a Pilot RCT
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- Sponsor
- Universitaire Ziekenhuizen KU Leuven · Academic / Other
- Sex
- Female
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Not accepted
Summary
Assessing whether Preimplantation Genetic Testing for Aneuploidy (PGT-A) can increase the ongoing pregnancy rate per transferred embryo and can decrease the time to pregnancy and miscarriage rate in patients with Recurrent Implantation Failure (RIF)
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | PGT-A | ovarian stimulation, oocyte aspiration, embryo culture until the blastocyst stage (day 5/6), TE biopsy, vitrification of all embryos in the blastocyst stage, PGT-A by NGS and finally embryo transfer of genetically normal embryos in cumulative frozen-thawed embryo transfer cycles |
| PROCEDURE | Control | ovarian stimulation, oocyte aspiration, embryo culture until the blastocyst stage, fresh embryo transfer of the morphologically best embryo on day 5/6, vitrification of supernumerary embryos and embryo transfer in cumulative frozen-thawed embryo transfer cycles if not pregnant from the fresh cycle. |
Timeline
- Start date
- 2019-05-01
- Primary completion
- 2025-12-31
- Completion
- 2026-12-31
- First posted
- 2019-04-03
- Last updated
- 2025-02-26
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT03900780. Inclusion in this directory is not an endorsement.