NCT03900013

Injectable Platelet Rich Fibrin With Demineralized Freeze-dried Bone Allograft in Treatment of Intraosseous Defects

Clinical and Radiographic Evaluation of Injectable PRF With Demineralized Freeze-Dried Bone Allograft (DFDBA) Compared to (DFDBA) in Treatment of Intraosseous Defects in Patients With Stage III Periodontitis: A Randomized Clinical Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 25 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Clinical and radiographic evaluation of injectable platelet rich fibrin (i-PRF) and demineralized freeze-dried bone allograft (DFDBA) compared to demineralized freeze-dried bone allograft (DFDBA) alone in management of intraosseous defects in stage III periodontitis patients.

Detailed description

Intraosseous defects are defined by the apical location of the periodontal pocket to the alveolar crest. In a recent radiographic study employing cone-beam computed tomography, a high prevalence of intraosseous defects 83% has been reported. Treatment of intraosseous defects is clinically challenging, as they often require complex regenerative periodontal therapy. Current regenerative techniques often employed in treatment of intraosseous defects demonstrate variation in improvement of clinical outcomes and degree of periodontal regeneration achieved.

Conditions

• Intrabony Periodontal Defect

Interventions

Type	Name	Description
PROCEDURE	Injectable platelet rich fibrin combined with DFDBA	The i-PRF will be mixed with bone graft then will be placed into the intraosseous defect
PROCEDURE	Demineralized Freeze Dried Bone Allograft	Demineralized Freeze Dried Bone Allograft alone will be placed into the intraosseous defect

Timeline

• Start date: 2019-09-20
• Primary completion: 2021-10-20
• Completion: 2021-12-20
• First posted: 2019-04-02
• Last updated: 2021-02-04

Locations

1 site across 1 country: Egypt