NCT03899389

Plasma TMAO (Trimethylamine N-oxide) as a Predictive Marker in Coronary Disease Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 600 (actual)
• Sponsor: Gdansk University of Physical Education and Sport · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The primary aim of the current research project is to determine whether the TMAO concentration in the blood can serve as a prognostic indicator of myocardial infarction. The hypothesis is that in patients with recent myocardial infarction, TMAO concentration in blood is higher than in patients undergoing scheduled coronarography.

Detailed description

To the study will be included volunteers - patients with stable angina (SA), who were scheduled for conventional coronary angiography, and patients with acute coronary syndrome (ACS) who were admitted to the hospital with chest pain and undergoing coronography surgery. Blood samples will be taken from volunteers once - before the coronography surgery by qualified medical personnel.

Conditions

• Coronary Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	plasma samples collection	Trimethylamine N-oxide (TMAO) concentration will be determined in plasma samples

Timeline

• Start date: 2017-02-01
• Primary completion: 2018-05-31
• Completion: 2018-05-31
• First posted: 2019-04-02
• Last updated: 2019-04-04

Locations

1 site across 1 country: Poland