Clinical Trials Directory

Trials / Completed

CompletedNCT03898752

Is Oxidative Stress in Semen Reduced by Lifestyle Intervention

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
31 (actual)
Sponsor
Peter Humaidan · Academic / Other
Sex
Male
Age
18 Years
Healthy volunteers
Not accepted

Summary

In this study we aim to investigate whether a 3-month life-style intervention would reduce oxidative stress (OS) in semen in men of infertile couples attending IVF-treatment. Men with a DFI above 15% (SCSA method) are recruited for intervention with a 3-month follow-up. It is hypothesized that men who also have a OS above 1.34 using a novel OS diagnostic method (MiOXSYS) respond better to antioxidant treatment with a change in OS and DFI. The primary outcome is the change in OS following the intervention. Secondary outcomes are morphological semen parameters and DNA fragmentation index.

Conditions

Interventions

TypeNameDescription
DIETARY_SUPPLEMENTOmega 3Omega 3: 1g daily for 3 months CoQ10: 100 mg daily for 3 months Multivitamin: 1 normal multivitamin tablet daily for 3 months

Timeline

Start date
2018-11-01
Primary completion
2020-05-01
Completion
2020-11-01
First posted
2019-04-02
Last updated
2021-03-22

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT03898752. Inclusion in this directory is not an endorsement.