NCT03898583

Clinical Trial to Assess Safety, Tolerability and the Pharmacodynamics Effect of Calcipotriol/Betamethasone Dipropionate in a New Administration Form in Subjects With Chronic Plaque Psoriasis.

A Phase 1b, Randomised, Controlled, Assessor-blinded Proof of Principle Trial to Assess Safety, Tolerability and Pharmacodynamics Effects of Microarray Patches Containing Calcipotriol/Betamethasone Dipropionate in Descaled Skin of Adults With Chronic Plaque Psoriasis Over a 21-day Treatment Period

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: LEO Pharma · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

To assess safety, tolerability and pharmacodynamics effect of treatment with microarray patches containing calcipotriol and betamethasone dipropionate.

Conditions

• Psoriasis Vulgaris

Interventions

Type	Name	Description
DRUG	Microarray patch A	Microarray patch
DRUG	Microarray patch B	Microarray patch
DRUG	Placebo	Microarray patch vehicle
DRUG	Daivobet	Daivobet Gel

Timeline

• Start date: 2019-04-15
• Primary completion: 2019-10-29
• Completion: 2019-10-29
• First posted: 2019-04-02
• Last updated: 2025-02-24

Locations

2 sites across 1 country: Germany