NCT03898440

Fetal Ano-genital Distance in 2D Ultrasound.

Using Anogenital Distance to Determinate Fetal Gender Beetween 18 et 41 Weeks of Gestation.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 318 (actual)
• Sponsor: University Hospital, Brest · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine a threshold value of fetal anogenital distance in 2D ultrasound to differentiate male fetuses from female fetuses, starting 18 weeks of gestation and until the due date. The study also evaluates the feasibility of the measure and its interobserver variability.

Detailed description

The anogenital distance of female newborns is shorter than that of male newborns. Urogenital disorders, such as hypospadias and micro-penis, are associated with a shorter anogenital distance. Anogenital distance is a good marker of fetal exposure to androgenic substances. Prenatal anogenital distance ultrasound measure can help the diagnosis in case of doubt about fetal sexual phenotype or in case of urogenital disorder suspicion (hypospadias or micropenis). Is the anogenital distance easy to make measure? Can this procedure be reproduced? What are the threshold values to determine fetal sex at each term of pregnancy?

Conditions

• Urogenital Abnormalities
• Prenatal Disorder
• Sex Development Disorder

Timeline

• Start date: 2019-04-15
• Primary completion: 2021-09-04
• Completion: 2021-09-04
• First posted: 2019-04-02
• Last updated: 2022-01-13

Locations

1 site across 1 country: France