NCT03898284

Impulse Oscillometry for Prognostication in Idiopathic Pulmonary Fibrosis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 54 (actual)
• Sponsor: University Hospital, Tours · Academic / Other
• Sex: All
• Age: 45 Years
• Healthy volunteers: Not accepted

Summary

A 5-point decline of forced vital capacity expressed as % predicted, over 6 months, is the current definition of disease progression (fast decline in lung function) in idiopathic pulmonary fibrosis. There is a need for techniques allowing to characterize disease progression earlier, so that treatment may be adapted as early as possible in the lack of a response. Hypothesis. Our hypothesis is that 3-month changes of lung function parameters measured by a novel technique, impulse oscillometry, predicts 6-month changes in forced vital capacity in idiopathic pulmonary fibrosis.

Detailed description

A 5-point decline of forced vital capacity expressed as % predicted, over 6 months, is the current definition of disease progression (fast decline in lung function) in idiopathic pulmonary fibrosis. There is a need for techniques allowing to characterize disease progression earlier, so that treatment may be adapted as early as possible in the lack of a response. Hypothesis. Our hypothesis is that 3-month changes of lung function parameters measured by a novel technique, impulse oscillometry, predicts 6-month changes in forced vital capacity in idiopathic pulmonary fibrosis.

Conditions

• Idiopathic Pulmonary Fibrosis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Impulse Oscillometry	Impulse Oscillometry will be performed in addition to usual care

Timeline

• Start date: 2019-04-23
• Primary completion: 2021-09-27
• Completion: 2021-09-27
• First posted: 2019-04-01
• Last updated: 2021-11-11

Locations

4 sites across 1 country: France