Clinical Trials Directory

Trials / Recruiting

RecruitingNCT03895593

Rescue Fecal Microbiota Transplantation for National Refractory Intestinal Infections

Rescue Fecal Microbiota Transplantation for Refractory Intestinal Infections: China National Registry

Status
Recruiting
Phase
Study type
Observational
Enrollment
100 (estimated)
Sponsor
The Second Hospital of Nanjing Medical University · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

A national data registry of patients receiving the rescue fecal microbiota transplantation for the refractory intestinal infections from the China Microbiota Transplantation System was designed to assess the short-term and long-term safety and efficacy.

Detailed description

This registry will enroll national patients with refractory intestinal infections (including clostridioides difficile infection, other infections with known or unknown pathogens) receiving rescue fecal microbiota transplantation (FMT) from the the China Microbiota Transplantation System. The improved methodology of FMT based on the automatic washing process and the related delivering consideration was named as washed microbiota transplantation (WMT) by the consensus statement from the FMT-standardization study group in 2019.12. Data of demographic characteristics, symptoms of intestinal infections, previous medicine treatment and clinical outcomes will be collected retrospectively abstracted from the electronic medical records or prospective follow-up. All the patients will be followed up for at least 12 weeks post-FMT. Information on follow-up will be designed to assess the short-term and long-term adverse events.

Conditions

Interventions

TypeNameDescription
OTHERrescue fecal microbiota transplantationFecal microbiota transplantation refers to the infusion of fecal microbiota from healthy donor into patients' gastrointestinal tract. The delivering ways for FMT include but are not limited to gastroscopy, colonoscopy, edema, nasogastric tube, transendoscopic enteral tube, and etc.

Timeline

Start date
2015-09-25
Primary completion
2024-05-01
Completion
2029-05-01
First posted
2019-03-29
Last updated
2024-02-29

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT03895593. Inclusion in this directory is not an endorsement.