Clinical Trials Directory

Trials / Approved For Marketing

Approved For MarketingNCT03895528

Lonafarnib for Patients With Hutchinson-Gilford Progeria Syndrome or Progeroid Laminopathy

A Treatment IND (Investigational New Drug) Protocol for EAP (Expanded Access Program) for the Use of Lonafarnib in Patients With Hutchinson-Gilford Progeria Syndrome (HGPS) or Progeroid Laminopathy

Status
Approved For Marketing
Phase
Study type
Expanded Access
Enrollment
Sponsor
Eiger BioPharmaceuticals · Industry
Sex
All
Age
12 Months
Healthy volunteers

Summary

This treatment IND protocol will allow patients with HGPS and progeroid laminopathies access to lonafarnib, the only compound shown to have an effect on the HGPS disease process resulting in improved outcomes (Gordon et al, 2018). There are no approved treatments for HGPS and progeroid laminopathies.

Conditions

Interventions

TypeNameDescription
DRUGLonafarnibFarnesyl transferase inhibitor

Timeline

First posted
2019-03-29
Last updated
2021-04-15

Source: ClinicalTrials.gov record NCT03895528. Inclusion in this directory is not an endorsement.