NCT03894176

Association of Plasma PTX3 Concentration and Outcomes of STEMI

Association of Plasma Pentraxin 3 Concentration With Angiographic and Clinical Outcomes in STEMI Treated by Primary Angioplasty

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 335 (actual)
• Sponsor: Indonesian Cardiovascular Research Center · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method. The angiographic and clinical outcomes were evaluated according to the PTX3 concentration.

Detailed description

335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method using human PTX3 kit. Blood was drawn at the emergency department before primary PCI. The angiographic and clinical outcomes were evaluated and analyzed according to the PTX3 concentration. The angiographic outcome were thrombus grade on initial angiogram and final TIMI flow. The clinical outcome were ECG resolution after primary PCI and all-cause death at 30 days. The plasma PTX3 concentration was then compared based on the outcomes.

Conditions

• STEMI
• Coronary; Ischemic

Interventions

Type	Name	Description
OTHER	Plasma PTX3 concentration	Long pentraxin 3, thrombus burden, final TIMI flow, ST segment resolution, STEMI, primary PCI

Timeline

• Start date: 2018-01-01
• Primary completion: 2018-08-02
• Completion: 2018-09-02
• First posted: 2019-03-28
• Last updated: 2019-03-28

Locations

1 site across 1 country: Indonesia