Trials / Completed
CompletedNCT03889210
β-hydroxybutyrate, Glucose Metabolism and Prediabetes
Cross-over, Placebo-controlled, Randomized Trial of β-hydroxybutyrate in Prediabetes
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 18 (actual)
- Sponsor
- University of Auckland, New Zealand · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The study aims to investigate changes in blood glucose metabolism after administration of a ketone ester drink.
Detailed description
New-onset prediabetes is the most significant risk factor for diabetes. Clinical studies in healthy human volunteers have demonstrated that ketone esters lower blood glucose levels in both fasting and fed state. Participants will visit the COSMOS clinic on two occasions and will be randomly allocated to receive either the HVMN ketone drink or placebo, in a cross-over design. Blood samples will be collected sequentially every 30 minutes for up to 150 minutes. Blood samples will be assayed for glucose and other markers of glucose metabolism.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | HVMN Ketone | Water-based, flavoured sport beverage |
| OTHER | Placebo | Water, stevia, malic acid, and thickening agent |
Timeline
- Start date
- 2019-04-01
- Primary completion
- 2019-08-16
- Completion
- 2019-08-30
- First posted
- 2019-03-26
- Last updated
- 2019-11-06
Locations
1 site across 1 country: New Zealand
Source: ClinicalTrials.gov record NCT03889210. Inclusion in this directory is not an endorsement.