NCT03886883

Endogenous Modulation of Pain and Stretch Tolerance

Endogenous Modulation of Pain - the Tolerance to Stretch

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 19 (actual)
• Sponsor: University College of Northern Denmark · Academic / Other
• Sex: Male
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This study investigates the role of two endogenous inhibitory mechanisms; exercise-induced hypoalgesia (EIH) and a conditioning painful stimulus (CPM) on passive joint range of motion, passive resistive torque and pain sensitivity. The study is a randomized, repeated-measures cross-over study.

Detailed description

The increase in range of motion following stretching is related to changes in the tolerance to stretch. The mechanistic relationships behind these changes in subject sensation are however unknown but could be related to endogenous modulation of pain.

Conditions

• Pain Threshold

Interventions

Type	Name	Description
OTHER	Exercise induced hypoalgesia (EIH)	An EIH response was induced by a 3-minute isometric contraction of the hand flexor muscles at 25% of maximal voluntary contraction (MVC).
OTHER	Static stretch (SS)	Two bouts of 30 seconds of static stretching (SS) of the knee flexors.
OTHER	Rest	The participants rested in a seated position for 10 minutes
OTHER	Conditioned pain modulation (CPM)	A CPM response was induced by way of the cold pressor test.

Timeline

• Start date: 2017-10-01
• Primary completion: 2017-12-30
• Completion: 2017-12-30
• First posted: 2019-03-22
• Last updated: 2019-03-26

Locations

1 site across 1 country: Denmark