NCT03885570

Blood Transfusion Management in Patients With Mitral Valve Replacement in China

Establishment of AI Prediction Model of Blood Transfusion Management in Patients With Mitral Valve Replacement

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 2,000 (estimated)
• Sponsor: The Third Xiangya Hospital of Central South University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The evaluation uses ΔHb as an independent factor combined with artificial intelligence (AI) to predict its impact on the prognosis and blood transfusion of patients undergoing cardiac surgery, thereby guiding perioperative clinical blood use and improving patient prognosis.

Detailed description

1. Select 8 hospitals to form a multi-center team, and enter the keyword "mitral valve replacement" in the case system of 8 hospitals to collect information on 2000 heart surgery patients. 2. Mainly collect information on preoperative, intraoperative and postoperative test indexes (blood routine, liver and kidney function, coagulation function, blood gas), cardiac color Doppler, blood transfusion and prognosis of patients undergoing cardiac surgery, using statistical methods for analysis. Identify key observations. 3. Gradually incorporate and exclude data, and use statistical methods to conduct preliminary analysis on the collected data. The AI prediction model was established by machine learning algorithm to predict intraoperative blood transfusion, verify the specificity and sensitivity of the blood transfusion prediction model, and scientifically guide clinical blood use.

Conditions

• Mitral Valve Replacement
• Transfusion Reaction
• Blood Transfusion Complication

Interventions

Type	Name	Description
PROCEDURE	Mitral valve replacement	Blood transfusion

Timeline

• Start date: 2019-09-16
• Primary completion: 2019-12-02
• Completion: 2021-12-31
• First posted: 2019-03-21
• Last updated: 2019-09-19

Locations

1 site across 1 country: China