NCT03885024

The Peer-Based Retention of People Who Use Drugs in Rural Research

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 850 (actual)
• Sponsor: Oregon Health and Science University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to, through several aims, test the effectiveness of peer-driven intervention and inform methods to optimize engagement in research in people who use drugs (PWUD) in rural America.

Detailed description

This study builds on the National Rural Opioids Initiative (NROI), a multi-state consortium studying access to care, overdose, and infectious consequences of opioid use disorder (OUD) in Rural America. It includes counties in rural Oregon and Appalachian Kentucky and Ohio with high rates of drug overdose. Aim 1: Conduct a randomized trial to evaluate the effectiveness of a peer-driven study retention intervention for retaining PWUD in Kentucky, Ohio, and Oregon Rural Opioid Initiative sites. Aim 2: Elicit preferences of PWUD in the Kentucky, Ohio, and Oregon Rural Opioid Initiative sites Aim 2a: Administer baseline survey of discrete choice experiment preferences for participating in clinical trials of potential medical innovations (e.g. new treatments for OUD, HIV, and HCV vaccination). Aim 2a will be accomplished as part of the NROI studies. The data will then be merged for PROUD-R² analyses. Aim 2b: Compare participant survey preferences regarding willingness to participate in clinical trials at baseline, 6, and 12 months. Aim 3: Explore participant perceptions of clinical research participation and retention among PWUD in rural America.

Conditions

• Drug Use
• Peer Influence

Interventions

Type	Name	Description
OTHER	Retention Video	Participants assigned to the retention training arm will watch a brief training video that will include information on how to retain peers in clinical trials.

Timeline

• Start date: 2020-08-31
• Primary completion: 2023-07-25
• Completion: 2023-07-25
• First posted: 2019-03-21
• Last updated: 2023-12-22

Locations

3 sites across 1 country: United States