Trials / Completed
CompletedNCT03881683
Determination of the Feasibility of Tumoural Somatic Mutations Detection in Blood of Patients With Ovarian Cancer
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 24 (actual)
- Sponsor
- Institut de Cancérologie de Lorraine · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
BOVARY-Pilot is a monocentric prospective transversal pilot study with a total duration of 6 months. The purpose of this study is to determine the feasibility of detecting somatic tumor mutations in the blood of patients with ovarian cancer in order to determine whether a blood test can replace a tissue biopsy to prescribe a personalized treatment. The method will consist of a single blood sample during the patient's visit and prior to the establishment of any newly diagnosed cancer treatment. The concordance of somatic mutations (SNV) found in tissue and in cell-free DNA (cfDNA) extracted from blood will then be compared
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | HRD and BRCA mutations | Compare BRCA1/2 and HRD genes mutation detected from blood sample (20 ml) and biopsy |
Timeline
- Start date
- 2020-02-21
- Primary completion
- 2021-02-19
- Completion
- 2021-02-19
- First posted
- 2019-03-19
- Last updated
- 2022-03-31
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT03881683. Inclusion in this directory is not an endorsement.