Trials / Unknown
UnknownNCT03880214
Prevalence of Chronic Oral Graft Versus Host Disease Risk Factors in Pediatric Patients
Cross Sectional Study Estimating the Prevalence and Predicting Risk Factors for Developing Chronic Oral Graft Versus Host Disease in Pediatric Patients Subjected to Hematopoietic Stem Cells Transplantation
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 250 (estimated)
- Sponsor
- yasmeen magdi sholkamy · Academic / Other
- Sex
- All
- Age
- 3 Years – 13 Years
- Healthy volunteers
- —
Summary
our aim is estimating the Prevalence and predicting risk factors for developing chronic oral graft versus host disease in pediatric patients subjected to hematopoietic stem cells transplantation
Detailed description
The study will be held in Children's Cancer Hospital Egypt for pediatric patients who underwent bone marrow transplantation. this study describes oral conditions, detect possible oral pathological manifestations and evaluate their prevalence as well as correlating it to assumed risk factor as age, sex, type of the transplant , previous acute attack of graft versus host disease and other organ involvement . A standardized Transplant Database Questionnaire will be completed Clinical examination will be performed then findings will be recorded for oral mucosal lesions , salivary flow rate in milliliter , mouth opening in milliimeter. Sample size estimation : The aim of this study is to screen pediatric patients at least three months after they undergo allogeneic hematopoietic stem cells transplantation to detect any risk factors for developing oral manifestations of chronic graft versus host disease during this period. Every patient fulfilling inclusion criteria in the hospital will be recruited consecutively in a period of six months starting from April 2019.
Conditions
Timeline
- Start date
- 2019-04-01
- Primary completion
- 2019-10-01
- Completion
- 2019-10-01
- First posted
- 2019-03-19
- Last updated
- 2019-03-20
Source: ClinicalTrials.gov record NCT03880214. Inclusion in this directory is not an endorsement.