Trials / Completed
CompletedNCT03879265
Validation of a NICS Method Using the Culture Medium
Validation of a Noninvasive Chromosome Screening (NICS) Method Using the Culture Medium
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (actual)
- Sponsor
- Instituto Bernabeu · Academic / Other
- Sex
- Male
- Age
- 19 Years – 49 Years
- Healthy volunteers
- —
Summary
This study aims to validate a non-invasive method of chromosomal screening (NICS), based on the Multiple Annealing and Looping Based Amplification Cycles- Next-generation Sequencing (MALBAC-NGS) technology, in order to determine the chromosomal endowment of a blastocyst from the DNA of the embryonic culture medium. The chromosomal status of the embryo from an embryo biopsy of trophoectoderm will be established (usual clinical practice), the chromosomal endowment from the DNA of the embryonic culture medium will be determined, and the results using the NICS and the conventional invasive method (Preimplantation Genetic Testing for Aneuploidy \[PGT-A\]) will be compared.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Noninvasive chromosome screening | Screening based on MALBAC-NGS technology |
Timeline
- Start date
- 2019-02-01
- Primary completion
- 2019-12-01
- Completion
- 2020-01-20
- First posted
- 2019-03-18
- Last updated
- 2020-08-10
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT03879265. Inclusion in this directory is not an endorsement.