Trials / Completed
CompletedNCT03878615
Inflammation and Organ Impact During Hepatic Surgery
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 18 (actual)
- Sponsor
- Sahlgrenska University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Monitoring of inflammatory substances (such as interleukins, CRP, albumine), and markers of organ dysfunction (such as creatinine, proenkephaline, amylase, troponine, IFABP and lactate) during elective liver resection. The study also includes monitoring of hemodynamic parameters, blood loss and postoperative complications. Results are to be used för power calculation for future trials.
Detailed description
During hepatic surgery, blood and urine samples will be obtained at 3 times during surgery, at 3 h after resection of liver, at 24 h after resection of liver and at post operative day 2, and subsequntly analyzed for the above mentioned substances. Routine labs will be monitored until patient is discharged from hospital. During surgery, hemodynamic parameters will be monitored by Picco calculations. Urine output and blood loss will be registred.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | elective surgery, according to deprtement routine | none, descriptive study |
Timeline
- Start date
- 2018-11-10
- Primary completion
- 2019-04-02
- Completion
- 2019-04-02
- First posted
- 2019-03-18
- Last updated
- 2025-04-27
Locations
1 site across 1 country: Sweden
Source: ClinicalTrials.gov record NCT03878615. Inclusion in this directory is not an endorsement.