NCT03878082

Propacetamol to Reduce Post Cesarean Section Uterine Contraction Pain

Perioperative Regular Usage of Propacetamol to Reduce Post Cesarean Section Uterine Contraction Pain and Opioid Consumption

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Mackay Memorial Hospital · Academic / Other
• Sex: Female
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

To evaluate that perioperative regular usage of propacetamol to reduce post cesarean section uterine contraction pain and opioid consumption

Detailed description

The most common method of pain control after cesarean section is intravenous patient-control analgesia (IVPCA) with morphine. Multimodal analgesia could improve the quality of perioperative pain control and reduceside effects of opioids. Previous researches marked that perioperative pain after cesarean section includes somatic wound pain and visceral uterine contraction pain. According to Academy of Breastfeeding Medicine, propacetamol is a safe pain-killer for an expectant mother and almost free from breast milk after intravenous injection. This study is a prospective double-blind randomized-controlled trial to evaluate that propacetamol could reduce visceral uterine contraction pain after cesarean section. Post cesarean section women will divide into three groups: 1. pain control with IVPCA for 2 days 2. pain control with IVPCA and propacetamol 1g every 6 hours for 2 days 3. pain control with IVPCA and propacetamol 2g every 6 hours for 2 days

Conditions

• Uterine Pain

Interventions

Type	Name	Description
DRUG	Propacetamol 1g	pain control with IVPCA and propacetamol 1g every 6 hours for 2 days
DRUG	Propacetamol 2g	pain control with IVPCA and propacetamol 2g every 6 hours for 2 days
DRUG	IVPCA	pain control with IVPCA

Timeline

• Start date: 2019-08-12
• Primary completion: 2022-12-30
• Completion: 2022-12-31
• First posted: 2019-03-18
• Last updated: 2023-03-15

Locations

1 site across 1 country: Taiwan