NCT03877354

Comparison of Tidal Volume Between Pediatric Anaesthesia and Paediatric Intensive Care Patients

Comparison of Tidal Volume Between Pediatric Anaesthesia and Paediatric Intensive Care Patients: Retrospective Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Brno University Hospital · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

Paediatric anaesthesiology and paediatric intensive care unit data will be retrospectively screened for the data regarding mechanical ventilation. The primary aim will be the tidal volume setting and the secondary the level of positive end-expiration pressure (PEEP) according to the inspired oxygen fraction (FIO2), and the level of driving pressure.

Detailed description

Protective positive pressure ventilation (tidal volume ≤6 mL/kg) in adult patients in intensive care is currently considered as a standard procedure. It is associated with a reduction of morbidity and positive outcome. In paediatric patients there are available only limited information related to the size of the tidal volume and it is recommended to use the volume between 5 and 8 mL per kg for the whole spectrum of ages of pediatric patients. The aim of this retrospective observational study is to evaluate the tidal volumes used in clinical practice in pediatric patients during general anesthesia and compared it to the tidal volumes used in paediatric critical care. Data will be harvested from the anaesthesiology records and from the paediatric intensive care unit charts. The tidal volume will calculated per kg of actual weight.

Conditions

• Protective Ventilation

Interventions

Type	Name	Description
OTHER	Data from anaesthesia records for ventilation setting screening	Data from anaesthesia records will be retrospectively screened for the ventilation settings
OTHER	Data from intensive care records for ventilation setting screening	Data from paediatric intensive care charts will be retrospectively screened for the ventilation settings

Timeline

• Start date: 2019-04-01
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2019-03-15
• Last updated: 2023-07-27

Locations

1 site across 1 country: Czechia