Trials / Completed
CompletedNCT03876821
Collect of Cord Blood From Subjects at Risk for Sickle Cell Disease, for the Purpose of Laboratory Research
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 44 (actual)
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France · Other Government
- Sex
- Female
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Not accepted
Summary
The study consists in collecting umbilical cord blood cells from newborns at risk of sickle cell disease, to perform laboratory experiments aiming to characterize the cells with HbS/HbS mutation, to develop methods to prepare, to gene-modify and to preserve these cells.
Detailed description
Pregnant individuals carrying at least one HbS allele will be included in the study to collect the umbilical cord blood of the child at birth. Collected cells will be used anonymously for genetic and bioexperimental laboratory research, aiming to develop autologous gene therapy for sickle cell disease.
Conditions
Timeline
- Start date
- 2019-10-23
- Primary completion
- 2023-10-23
- Completion
- 2023-10-23
- First posted
- 2019-03-15
- Last updated
- 2025-11-18
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT03876821. Inclusion in this directory is not an endorsement.